Endocrine deficit after fractionated total body irradiation.

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چکیده

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Endocrine deficit after fractionated total body irradiation.

Endocrine function was assessed in 31 children (17 boys) after fractionated total body irradiation used in the preparative regimen for bone marrow transplantation. Endocrine dysfunction was present in 25 children. Fifteen of 29 had growth hormone insufficiency 0.9-4.9 years after total body irradiation, yet only three of the 15 had received previous cranial irradiation. Five of 30 had thyroid d...

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Waldenstrom’s Macroglobulinemia treated with fractionated low-dose total body irradiation

Case Report: A 78-year-old male with relapsed Waldenstrom’s macroglobulinemia following therapy with chlorambucil underwent a five-week course of TBI. The total dose delivered was 1.5 Gy, given as 0.15 Gy twice weekly for ten sessions. During the course of therapy his CD4 cells increased from 637 (cells/mm3) to 808 partly through treatment and then declined to 654 at the completion of therapy. ...

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Factors associated with pulmonary toxicity after myeloablative conditioning using fractionated total body irradiation

PURPOSE Pulmonary toxicities, including infectious pneumonia (IP) and idiopathic pneumonia syndrome (IPS), are serious side effects of total body irradiation (TBI) used for myeloablative conditioning. This study aimed to evaluate clinical factors associated with IP and IPS following TBI. MATERIALS AND METHODS Fifty-eight patients with hematologic malignancies who underwent TBI before allogene...

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Recovery of spermatogenesis after total-body irradiation.

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Papillary thyroid carcinoma after total body irradiation.

Two children developed papillary thyroid carcinoma after allogeneic bone marrow transplantation (BMT) probably due to radiotherapy during remission and pretransplantation conditioning. Establishing a relationship between the cellular thyroid stimulating hormone (TSH) effect and development of carcinoma in cases with high serum TSH concentrations is difficult. After BMT, patients should be regul...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 1992

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.67.9.1107